Ecopathology of Ranaviruses Infecting Amphibians

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Ecopathology of Ranaviruses Infecting Amphibians

Ranaviruses are capable of infecting amphibians from at least 14 families and over 70 individual species. Ranaviruses infect multiple cell types, often culminating in organ necrosis and massive hemorrhaging. Subclinical infections have been documented, although their role in ranavirus persistence and emergence remains unclear. Water is an effective transmission medium for ranaviruses, and survi...

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Although viruses infecting and affecting humans are the focus of considerable research effort, viruses that target other animal species, including cold-blooded vertebrates, are receiving increased attention. In part this reflects the interests of comparative virologists, but increasingly it is based on the impact that many viruses have on ecologically and commercially important animals. Frogs a...

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Evaluation of a polyclonal antibody for the detection and identification of ranaviruses from freshwater fish and amphibians.

A rabbit polyclonal antibody (PAb) raised against European catfish virus (ECV; isolated from black bullhead Ameiurus melas in France) was produced and then evaluated using a panel of 9 ranavirus isolates collected from different lower vertebrate species originating from Australia, North and South America, Southeast Asia, and Europe. Using ranavirus-infected epithelioma papillosum cyprini (EPC) ...

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Ecology and pathology of amphibian ranaviruses.

Mass mortality of amphibians has occurred globally since at least the early 1990s from viral pathogens that are members of the genus Ranavirus, family Iridoviridae. The pathogen infects multiple amphibian hosts, larval and adult cohorts, and may persist in herpetofaunal and osteichthyan reservoirs. Environmental persistence of ranavirus virions outside a host may be several weeks or longer in a...

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Ranaviruses (family Iridoviridae) were discovered serendipitously during an attempt to generate frog kidney cell cultures for the propagation of Lucke herpesvirus, an oncogenic herpesvirus [1]. Unexpectedly, some cultures displayed spontaneous cytopathic effect suggestive of a viral infection. Frog virus (FV)-1 and -2 were recovered from normal kidneys, whereas FV3, isolated from a frog with re...

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ژورنال

عنوان ژورنال: Viruses

سال: 2011

ISSN: 1999-4915

DOI: 10.3390/v3112351